Fujifilm GFX 50S vs Canon EOS R6 Mark II

This is a full comparison between the cameras Fujifilm GFX 50S and Canon EOS R6 Mark II. We compare them by looking at the categories you see below.

Fujifilm GFX 50S

Canon EOS R6 Mark II

Manufacturing

Fujifilm GFX 50S is manufacturered by Fujifilm but Canon EOS R6 Mark II is from Canon. Both Fujifilm and Canon are well known brands though.

Fujifilm GFX 50S were released 2016 and Canon EOS R6 Mark II was released 2022. That is a 6 years difference. In tech, this period can be of interest since technology is always improving, etc.

Camera	Released
Fujifilm GFX 50S	2016
Canon EOS R6 Mark II	2022

Type of camera

Both these cameras are Mirrorless cameras. No difference there.

Sensors / crop factor

These cameras have different sensors. Fujifilm GFX 50S has a "Fujifilm Medium Format"-sensor while Canon EOS R6 Mark II has a "Canon Full Frame"-sensor, and their difference in sensors will also affect the crop factor and experience focal length. See the table below.

Camera	Focal length, 50mm f/1.8 **
Fujifilm GFX 50S	39.5 mm Fujifilm Medium Format sensor Crop factor/focal length multiplier by * 0.79
Canon EOS R6 Mark II	50 mm Full-frame sensor No crop factor/focal length multiplier

** Experienced focal length when using a lens such as a common "50mm f/1.8"

Learn more about crop factor and focal length multiplier here:

Resolution

Fujifilm GFX 50S has a 51 MP (Megapixels) resolution while Canon EOS R6 Mark II has 24 MP. If we break down this in more detail this is the data behind the numbers:

Camera	Megapixels
Fujifilm GFX 50S	51 MP 51121152 pixels 8256 x 6192
Canon EOS R6 Mark II	24 MP 24000000 pixels 6000 x 4000

Fujifilm GFX 50S has a 113 % larger resolution than Canon EOS R6 Mark II. This could give you more details in the picture but also a possibility to crop more in the pictures, afterward while editing the pictures, if needed that is.

ISO range

Canon EOS R6 Mark II has a larger ISO-range than Fujifilm GFX 50S. Canon EOS R6 Mark II has an ISO range that stretches from 100 to 102400 while Fujifilm GFX 50S has 100 to 12800.

Camera	ISO Range
Fujifilm GFX 50S	100-12800
Canon EOS R6 Mark II	100-102400

Autofocus and lens compatibility

Both of these cameras have a built-in autofocus motor. Some lenses, that support autofocus, do not have an autofocus motor of their own but this won't cause any problems with these two cameras.

Worth mentioning is that Canon EOS R6 Mark II belongs to the Canon EOS R-system and needs an adapter to work with Canons EF, EF-S, MP-E, and TS-E lenses. You can read more about this adapter here:
Canon Lens Mount Adapter EF-EOS R

Here is a complete overview of which lenses work with each camera:
Lens compatibility chart for Fujifilm GFX 50S
Lens compatibility chart for Canon EOS R6 Mark II

Pictures per second

Depending on what you are shooting the FPS, or frames/pictures per second, can definitely be of interest. Fujifilm GFX 50S can shoot up to 3 pictures per seconds and Canon EOS R6 Mark II can shoot up to 40 pictures per seconds.

Camera	FPS (Frames per second)
Fujifilm GFX 50S	3
Canon EOS R6 Mark II	40

Ability to record movies

It is becoming more and more popular to record movies with digital cameras.

In this case, both Fujifilm GFX 50S and Canon EOS R6 Mark II can shoot movies.

Weight

The weight of the camera can be an extremely important factor, especially if the camera is about to be used, or carried around, for several hours at a time.

Fujifilm GFX 50S weighs 920 gr (equal to 2.03 lb) which is 37% heavier than Canon EOS R6 Mark II and its 670 gr (or 1.48 lb).

Camera	Weight
Fujifilm GFX 50S	920 gr 2.03 lb
Canon EOS R6 Mark II	670 gr 1.48 lb